PHASAGE

PhasAGE – Excellence Hub on Phase Transitions in Aging and Age-Related Disorders

networking

PhasAGE consortium is centrally positioned in a network of academic, industry, healthcare, and policymaker stakeholders.

The synergies already established with ongoing collaborative projects and with National and European research infrastructures will promote better access to relevant disease databases and research networks. The establishment of a sustainable framework will promote novel research interfaces benefiting both IBMC/i3S and the partner’s institutions.

Throughout the project duration, the PhasAGE consortium is committed to expanding this network and strengthen the links with international research consortia and scientific infrastructures. 

NETWORK2

COLLABORATIVE PROJECTS

H2020 TWINNING PROJECTS

IMpaCT – Imaging life from Molecules to cells

Project Coordinator: ITQB-Nova, PT | Grant agreement No 857203

The project aims at building knowledge on Cryo-EM methodologies at ITQB NOVA (PT). The interaction with IMpaCT will complement the expertise of the PhasAGE team on CryoEM. Both projects will benefit the institutions by increasing the impact and visibility of Structural Biology and Biophysics at the national and European level. 

REMODEL – Research Models in Infection, Cancer and Tissue Regeneration

Project Coordinator: IBMC/i3S, PT | Grant agreement No 857491

The project aims to capacitate IBMC/i3S with innovative model systems that can replace animal experiments for translational research. PhasAGE and REMODEL will build a solid interdisciplinary framework to go from molecular driven research to translational applications with advanced organoid in vitro models. 

H2020 MCSA RISE PROJECTS

REFRACT – Repeat protein Function, Refinement, Annotation and Classification of Topologies

Project Coordinator: UNIPD, IT | Grant agreement No 823886

REFRACT aims to extend our knowledge on the mechanism of tandem repeat protein (TRP) function and evolution, establishing a common classification and best practices. The resulting guidelines for classification, functional characterization and experimental analysis of repeat proteins and aggregation-prone sequences will directly feed into PhasAGE scientific activities, benefiting all participating research teams. 

IDPfun – Driving the functional characterization of Intrinsically Disordered Proteins

Project Coordinator: UNIPD, IT | Grant agreement No 778247

The IDPfun consortium aims to research novel ways to detect and characterize different IDP phenomena in their evolutionary context. By developing ontologies and classification, it intends to facilitate the comprehension of IDP complexity and understand IDP functional mechanisms in several biological processes and in the context of disease. The resulting achievements will leverage PhasAGE research activities, benefiting all participating research teams. 

RESEARCH INFRASTRUCTURES

EUROPEAN INFRASTRUCTURES

ELIXIR_logo_standard
ELIXIR_idp_logo

ELIXIR EuropeESFRI Research Infrastructure for life science data support the Intrinsically Disordered Proteins (IDP) Community

The ELIXIR Europe supports IDP Community that aims to define standards, tools and resources to accelerate the identification, analysis and functional characterisation of IDPs.  A better understanding of IDR-mediated interactions and their structure and function will help in developing new therapeutic strategies to treat human diseases.

*ELIXIR is partly funded by the European Commission within the Research Infrastructures programme of Horizon 2020.

ACKNOWLEDGEMENT – INFORMATION ON EU FUNDING 

All major results, communication and dissemination activities carried under PhasAGE funding must acknowledge the support of the EU funding with the following statement, possibly accompanied by the EU logo: 

  • For communication activities: “This project has received funding from European Union’s Horizon 2020 research and innovation programme under grant agreement No 952334.”
  • For infrastructure, equipment and major results: “This [infrastructure][equipment][insert type of result] is part of a project that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 952334.”

The PhasAGE logo and EU emblem with funding description should be used whenever possible. If necessary, you can require this information by sending a message to phasageproject@i3s.up.pt.