PhasAGE – Excellence Hub on Phase Transitions in Aging and Age-Related Disorders


The Toolbox gathers computational online resources and experimental protocols to study protein phase separation. It serves the scientific community and industry stakeholders by sharing websites, online platforms – databases and prediction algorithms tools – and guidelines for the study of protein phase separation. Part of these computational tools and databases were developed by members of the PhasAGE consortium in a collaborative effort for advancing computational biology and bioinformatics research. 

Database of proteins driving liquid-liquid phase separation in living cells

Database of intrinsically disordered proteins

Database of protein disorder and mobility annotations

Database of annotated tandem repeat protein structures

Prediction of protein liquid-liquid phase separation

Prediction of repetitive structures and units in tandem repeat proteins

Predictor for Amyloid STructural Aggregation

Protein SOlubility based on Disorder and Aggregation Predictor

Prediction of “hot spots” of aggregation in polypeptides

Prediction of aggregation propensity in protein structures and rational design of protein solubility

Protein disorder predictor over pH for IDPs/IDRs

Predictor for aggregation propensity of IDPs based on the environment pH