PHASAGE

PhasAGE – Excellence Hub on Phase Transitions in Aging and Age-Related Disorders

PUBLICATIONS

A list of references from members of the consortium and other scientific communities to support research in the field of phase separation in aging and disease.

  • Vendruscolo M, Fuxreiter M. “Sequence Determinants of the Aggregation of Proteins Within Condensates Generated by Liquid-liquid Phase Separation.” J Mol Biol. 2021. doi: 10.1016/j.jmb.2021.167201 Link 2 Icon - Free Icons
  • Korkmazhan E, Tompa P, Dunn AR. “The role of ordered cooperative assembly in biomolecular condensates.” Nat Rev Mol Cell Biol. 2021 Aug 4 Link 2 Icon - Free Icons
  • Parisi G, Palopoli N, Tosatto SCE, Fornasari MS, Tompa P. “Protein” no longer means what it used to.” Curr Res Struct Biol. 2021 Jul 7;3:146-152 Link 2 Icon - Free Icons
  • Díaz-Caballero M, Navarro S, Ventura S. “Functionalized Prion-Inspired Amyloids for Biosensor Applications.” Biomacromolecules. 2021 Jul 12;22(7):2822-2833 Link 2 Icon - Free Icons
  • Quaglia F, Lazar T, Hatos A, Tompa P, Piovesan D, Tosatto SCE. “Exploring Curated Conformational Ensembles of Intrinsically Disordered Proteins in the Protein Ensemble Database.” Curr Protoc. 2021 Jul;1(7):e192 Link 2 Icon - Free Icons
  • Pintado C, Santos J, Iglesias V, Ventura S. “SolupHred: a server to predict the pH-dependent aggregation of intrinsically disordered proteins.” Bioinformatics. 2021 Jul 12;37(11):1602-1603 Link 2 Icon - Free Icons
  • Fuxreiter M, Vendruscolo M. “Generic nature of the condensed states of proteins.” Nat Cell Biol. 2021 Jun;23(6):587-594. Link 2 Icon - Free Icons
  • Santos J, Gracia P, Navarro S, Peña-Díaz S, Pujols J, Cremades N, Pallarès I, Ventura S. “α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity.” Nat Commun. 2021 Jun 18;12(1):3752 Link 2 Icon - Free Icons
  • Necci M, Piovesan D; CAID Predictors; DisProt Curators, Tosatto SCE. “Critical assessment of protein intrinsic disorder prediction.” Nat Methods. 2021 May;18(5):472-481 Link 2 Icon - Free Icons
  • Pinheiro F, Santos J, Ventura S. “AlphaFold and the amyloid landscape.” J Mol Biol. 2021 May 21:167059 Link 2 Icon - Free Icons
  • Monzon AM, Bonato P, Necci M, Tosatto SCE, Piovesan D. “FLIPPER: Predicting and Characterizing Linear Interacting Peptides in the Protein Data Bank.” J Mol Biol. 2021 Apr 30;433(9):166900 Link 2 Icon - Free Icons
  • Pakravan D, Michiels E, Bratek-Skicki A, De Decker M, Van Lindt J, Alsteens D, Derclaye S, Van Damme P, Schymkowitz J, Rousseau F, Tompa P, Van Den Bosch L. “Liquid-Liquid Phase Separation Enhances TDP-43 LCD Aggregation but Delays Seeded Aggregation.” Biomolecules. 2021 Apr 8;11(4):548 Link 2 Icon - Free Icons
  • Fuxreiter M. “Spot in a drop: mutations in aberrant condensates.” Nat Rev Mol Cell Biol. 2021 Mar;22(3):162-163 Link 2 Icon - Free Icons
  • Farahi N, Lazar T, Wodak SJ, Tompa P, Pancsa R. “Integration of Data from Liquid-Liquid Phase Separation Databases Highlights Concentration and Dosage Sensitivity of LLPS Drivers.” Int J Mol Sci. 2021 Mar 16;22(6):3017 Link 2 Icon - Free Icons
  • Piovesan D, Necci M, Escobedo N, Monzon AM, Hatos A, Mičetić I, Quaglia F, Paladin L, Ramasamy P, Dosztányi Z, Vranken WF, Davey NE, Parisi G, Fuxreiter M, Tosatto SCE. “MobiDB: intrinsically disordered proteins in 2021.” Nucleic Acids Res. 2021 Jan 8;49(D1): D361-D367 Link 2 Icon - Free Icons
  • Van Lindt J, Bratek-Skicki A, Nguyen PN, Pakravan D, Durán-Armenta LF, Tantos A, Pancsa R, Van Den Bosch L, Maes D, Tompa P. “A generic approach to study the kinetics of liquid-liquid phase separation under near-native conditions.” Commun Biol. 2021 Jan 19;4(1):77 Link 2 Icon - Free Icons
  • Hardenberg M, Horvath A, Ambrus V, Fuxreiter M, Vendruscolo M. “Widespread occurrence of the droplet state of proteins in the human proteome.” Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33254-33262 Link 2 Icon - Free Icons
  • Bratek-Skicki A, Pancsa R, Meszaros B, Van Lindt J, Tompa P. “A guide to the regulation of the formation of biomolecular condensates.” FEBS J. 2020 May;287(10):1924-1935 Link 2 Icon - Free Icons
  • Barroso-Vilares M, Macedo JC, Reis M, Warren JD, Compton D, Logarinho E. “Small-molecule inhibition of aging-associated chromosomal instability delays cellular senescence.” EMBO Rep. 2020 May 6;21(5):e49248 Link 2 Icon - Free Icons

ACKNOWLEDGEMENT – INFORMATION ON EU FUNDING 

Please use the following statement to acknowledge the PhasAGE  participation in collaborative publications: 

“This [insert type of result] is part of a project that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 952334.”