PhasAGE – Excellence Hub on Phase Transitions in Aging and Age-Related Disorders
Training SCHOol 1
Computational Methods to Study Protein Phase Separation
The Training School “Computational Methods to Study Protein Phase Separation” is the first edition of a series of PhasAGE training activities.
Participants will receive training in a multidisciplinary environment, and acquire knowledge on integrative methodologies required to study phase transitions in vitro and in cells.
The goal of this course is to provide participants with the basic knowledge to understand the phenomenon of Phase Separation, its role in biological processes and diseases. In addition, the course will provide an overview of the available computational resources to navigate this knowledge. Participants will have hands-on training in tools and resources available for life sciences, to collect information from the literature on biomolecular phase transitions, identify features triggering phase transitions, mutations associated with diseases, known or predicted PTMs and molecular interaction sites.
University of Padova (Italy)
Prof. Silvio Tosatto (University of Padova)
Dr. Lisanna Paladin (University of Padova)
Dr. Alex Monzon (University of Padova)
Dr. Federica Quaglia (University of Padova)
Diana Battistella (University of Padova)
phase separation, protein structure, protein aggregation, disordered proteins, repeated proteins, protein interactions, protein function, biological processes, diseases, aging
TARGET AUDIENCE AND REQUIREMENTS
This course is intended for Master students, PhD students and young researchers that have a basic understanding of protein structure and function and the cell system. Participants are not required to have computational or programming skills, but to be familiar with the navigation of online biological resources.
Some sessions will be open to the public for attendance. Practical sessions are limited to 25 attendees to maximize active learning. Participants will be selected based on their CV and motivation statement and will receive a certificate of completion.
Requirements – A stable internet connection, experience in an operating system and a Internet browser.
Prof. Sandra Macedo Ribeiro (University of Porto, Portugal)
Prof. Peter Tompa (VIB-VUB, Belgium)
Prof. Salvador Ventura (Autonomous University of Barcelona, Spain)
Prof. Zsuzsanna Dosztanyi (Eötvös Loránd University, Hungary)
Prof. Vasilis Promponas (University of Cyprus, Cyprus)
Prof. Silvio Tosatto (University of Padova, Italy)
Prof. Antonio Trovato (University of Padova, Italy)
Dr. Sonia Longhi (Center for the National Scientific Research – France)
Dr. Balint Meszaros (European Molecular Biology Laboratory – Germany)
Dr. Alex Monzon (University of Padova, Italy)
Dr. Federica Quaglia (University of Padova, Italy)
Course duration – 13 hours 15 minutes
Course and registration are free of charge. PhasAGE will not cover any expenses incurred by the participants.
In collaboration with
REFRACT has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 823886.
IDPfun has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 778247
The ELIXIR-Europe Intrinsically Disordered Proteins Community
SIB – Società Italiana di Biochimica e Biologia Molecolare
PhasAGE is a Twinning project fully committed to gender balance by developing and supporting a diverse and inclusive community.